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KemetiCare Research Institute

Evidence that reflects the people it is meant to serve.

Clinical trials and real-world evidence registries have long underrepresented diverse, melanin-dominant populations. The Institute exists to close that evidence gap — generating trusted, real-world, ethnospecific evidence with the communities research has historically left out.

The evidence gap

Why ethnospecific research matters.

Most of the evidence behind modern prevention and treatment comes from study populations that do not reflect the people who carry the greatest burden of chronic disease.

When the data is narrow, precision medicine is narrow too. One-size-fits-all care misses cultural, social and biological differences that shape how people live, respond and persist with care.

Ethnospecific research captures that missing context — so programs, products and policy can be designed for the people they are meant to serve.

Methodology

Six Research Pillars.

Every Institute study follows the same standardized framework, so findings can be compared across sites and communities.

  1. Population Intelligence

    Collects demographic, social, cultural, behavioral and biometric context — moving beyond simple racial categories to capture real lived experience.

  2. Behavioral & Wellness Profiling

    Uses the KemetiCare Score to make wellness readiness and behavioral context a measurable research variable, organized around the Seven Principles.

  3. Intervention Tracking

    Documents exposure to education, health coaching, nutrition support, autonomic assessment and faith-based support, so real-world context is part of the record.

  4. Outcome Measurement

    Tracks what people feel — stress, sleep quality, confidence — alongside objective measures such as blood pressure, glucose markers and persistence with care.

  5. Digital Engagement Analytics

    Studies how people interact with onboarding, reminders and coaching cadence, to learn what helps people stay engaged over time.

  6. Translation & Dissemination

    Turns findings into community reports, white papers, institutional proposals and peer-reviewed publications — returning knowledge to the communities that made it possible.

Flagship initiative

The PILLAR Network

Prospective Incretin Longitudinal Lifestyle and Autonomic Registry. PILLAR is the Institute's flagship cardiometabolic initiative. Incretin-based medicines have shown strong results in large pivotal trials. The open questions now are real-world ones: which populations persist with treatment, which delivery models keep people engaged, and what happens outside major academic centers.

  • Who stays on treatment in real community settings — and why do people stop?
  • How do lifestyle, culture, stress and autonomic balance shape cardiometabolic outcomes?
  • Which models of support help people sustain progress beyond the first months?
ActiveQuezon City, Philippines

PILLAR-PH

PILLAR-PH is the inaugural deployment of the PILLAR Network: a prospective, single-site, non-interventional registry studying real-world incretin access, persistence and cardiometabolic outcomes, with an embedded biomarker substudy. As the largest city in the National Capital Region, Quezon City carries a substantial urban cardiometabolic burden, while Filipino populations remain underrepresented in global clinical research.

Design
Prospective, observational, standard-of-care registry
Participants
Adults meeting Asia-Pacific risk thresholds, enrolled at treatment start
Follow-up
Baseline, 12 weeks, 24 weeks, optional 52 weeks
Primary focus
Weight change and medication persistence at 24 weeks

What the registry measures

  • Hemoglobin A1c and fasting glucose
  • Waist circumference and systolic blood pressure
  • Side effects and reasons for stopping treatment
  • Appetite, functional capacity and treatment satisfaction
  • Exploratory autonomic markers (TM Flow) and insulin resistance

As an observational registry, PILLAR-PH follows the local ethics-review pathway overseen within the Philippine Health Research Ethics Board framework, with disciplined informed consent.

Global network

One standard, many communities.

PILLAR-PH is the first deployment. Each future site is designed to use the same infrastructure and assessment protocol, building a comparable, cross-community dataset.

  • PILLAR-US

    African American communities (Dallas–Fort Worth and Houston)

  • PILLAR-NG

    Nigerian and West African populations

  • PILLAR-GH

    Ghanaian populations

  • PILLAR-JA

    Jamaican and Caribbean diaspora

  • PILLAR-PNG

    Papua New Guinean populations

  • PILLAR-FJ

    Fijian populations

  • PILLAR-WS

    Samoan populations

  • PILLAR-MH

    Marshallese populations

Future sites are part of the network design and open as local partnerships and ethics approvals are established.

How the work is organized

Three connected entities, one mission.

KemetiCare Ethnospecific Research Institute LLC

The scientific and operational engine — manages sites, executes protocols, collects data and delivers research outputs.

KemetiCare Health Equity Initiative

The community engagement arm — supports community wellness programs and faith-based participation.

KemetiCare Foundation

The academic and public-funding arm, designed for institutional and philanthropic research partnerships.

The Institute operates as a specialized Site Management Organization (SMO). It supports community clinical sites with study start-up, workflow design, staff training, consent materials, data capture, participant engagement and publication planning — so local clinicians stay the face of care while the Institute provides the research infrastructure.

Learning loop

Insight that returns to the community.

Engagement, measurement and research feed better programs — and better programs feed better engagement.

  1. Engagement
  2. Measurement
  3. Data
  4. Research
  5. Insight
  6. Better Programs
  7. Better Engagement
  8. Improved Health Outcomes

Improved Health Outcomes return to Engagement

Work with us

Who the Institute partners with.

Clinical sites and investigators

Community clinics and physicians who want research infrastructure without losing their role as the face of care.

Academic collaborators

Researchers working on health equity, community-based participatory research and real-world evidence.

Sponsors and funders

Organizations seeking real-world evidence from populations that conventional datasets under-sample.

Communities

Faith communities and community organizations that want research done with them, not to them.

One connected system

How this connects

Outcome

Improve health outcomes

Through

the pursuit of Optimal Wellness

While

working to understand and reduce persistent health disparities